Expanding interest in nuclear power and advanced fuel cycles indicate that use of mixed-oxide (MOX) fuel in the current and new U.S. reactor fleet could become an option for utilities in the coming decades. In light of this renewed interest, EPRI has reviewed the substantial knowledge base on MOX fuel irradiation in light water reactors (LWRs). The goal was to evaluate the technical feasibility of MOX fuel use in the U.S. reactor fleet for both existing and advanced LWR designs (Generation III/III+).

Following the proposals for nuclear fuel assurance of International Atomic Energy
Agency (IAEA) Director General Mohamed ElBaradei, former Russian President Vladimir V.
Putin, and U.S. President George W. Bush, joint committees of the Russian Academy of
Sciences (RAS) and the U.S. National Academies (NAS) were formed to address these and other
fuel assurance concepts and their links to nonproliferation goals. The joint committees also
addressed many technology issues relating to the fuel assurance concepts. This report provides